Aripiprazole general information

How to buy online (Abilify) Aripiprazole.

Indications for use of the drug Aripiprazole (Abilify):

Prescribers Abilify (Aripiprazole) for the acute treatment of schizophrenia, as well as maintenance therapy.
The drug is given if you have acute manic episodes of bipolar I disorder, as well as for maintenance treatment in patients with bipolar I disorder who have recently had manic or mixed episode.

The active ingredient of the drug Abilify - "Aripiprazole". Application Aripiprazole should be agreed with your physician. Aripiprazole - antipsychotic, neuroleptic.

Formulation Aripiprazole - pills.

Dosing and Administration Aripiprazole:

Ingest, regardless of the meal, 1 times a day with a glass of pure water.

In schizophrenia:

starting dose of 10-15 mg per day maintenance dose - 15 mg per day.
in clinical studies demonstrated the efficacy of the drug in doses of 10 to 30 mg per day.

During manic episodes:
dose of 15-30 mg per day. taking for 3-12 weeks.

When bipolar disorder: dose correction is performed at intervals of not less than 24 hours, clinical studies demonstrated the efficacy of the drug in doses of 15-30 mg per day. Dose adjustment in patients older than 65 years are required.

Aripiprazole - pharmacological effects:

Neuroleptics. The therapeutic effect of Aripiprazole in schizophrenia is caused by a combination of partial agnostic activity on dopamine D2 and 5HT1A serotonin receptors. Just antagonistic activity against serotonin 5HT2 receptors.

Aripiprazole possesses high in vitro affinity for dopamine D2 and D3 receptors 5HT1A and 5HT2A serotonin receptors. Identical, D4 dopamine, serotonin 5HT2C and 5NT7, ​​alpha 1-adrenoceptor and histamine H1 receptors.

Aripiprazole is characterized by moderate similarity with serotonin reuptake sites and the lack of affinity for muscarinic receptors. Aripiprazole in animal experiments showed antagonism of dopaminergic hyperactivity. There was a display of dopaminergic agonism against ISU activity.

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